Ngwaahịa
Retinoic acid
Usoro nhazi
Ọdịdị:Ìhè oroma ma ọ bụ odo crystalline ntụ ntụ
Njupụta:1.0597 (atụmatụ siri ike)
Ebe mgbaze:180-181°C (ọkụ)
Ebe esi nri:381.66°C (atụmatụ siri ike)
Refractivity:1.4800 (atụmatụ)
Data nchekwa
izugbe
Ngwa
Retinoic acid (tretinoin) bụ ihe sitere na vitamin A.Ọ egosipụtala ikike ịgbanwe njikọ nke collagen, mụbaa ọkwa hyaluronic acid dermal, ma kpalie uto fibroblast na matrix extracellular.A na-eji ya maka ọrịa keratinization na maka ịgwọ ihe otutu.
Vitamin A, nke nwere usoro molekụla C20H28O2, bụ ngwaahịa etiti nke vitamin A n'ime ahụ, na-emetụta uto ọkpụkpụ ma na-akwalite mmetụta metabolic nke mmụba cell epithelial, ọdịiche na keratinolysis.A na-eji ya maka ọgwụgwọ nke otutu vulgaris, psoriasis, ichthyosis, lichen planus, furunculosis na-acha uhie uhie, follicular keratosis, squamous cell carcinoma na melanoma.
Udi: Mgbochi akpụkpọ keratinization na-adịghị mma, cell na-ebute ihe dị iche iche.
Ọnọdụ nchekwa: ọkụ na-ekpuchi ọkụ na akara
Retinoic acid enweghị mmetụta na ọrụ tyrosinase na melanin nke melanocytes mmadụ nkịtị.Mgbe akpụkpọ ahụ na-eme agadi physiological ma ọ bụ mebie ya site na ọgwụ ọjọọ, UV radieshon ma ọ bụ trauma, retinoic acid na-edozi ma ọ bụ na-egbochi ihe na-adịghị mma na nhazi biochemical na nhazi morphological nke anụ ahụ njikọ dermal kpatara ihe ndị na-emerụ ahụ.Retinoic acid anaghị enwe mmetụta na njikọ collagen nkịtị nkịtị.Na mgbakwunye, retinoic acid nwere ọrụ mgbochi na leukocyte chemotaxis, si otú a na-eme ihe dị ka onye na-egbochi mkpali.Retinoic acid enweghị mmetụta kpọmkwem na gland sebaceous na nzuzo ha.
