Ngwaahịa
Orlistat
Usoro nhazi
Njirimara anụ ahụ
Ọdịdị: ọcha crystalline ntụ ntụ
Njupụta: 0.976±0.06
Ebe mgbaze:<50°C<br /> Ebe esi mmiri: 615.9±30.0°C
Data nchekwa
Ụdị ihe egwu: ngwa ahịa izugbe
Ngwa
Ngwakọta nri obere kalori dị ala dabara adaba maka ọgwụgwọ ogologo oge nke ndị buru oke ibu na ndị buru oke ibu, gụnyere ndị mepụtara ihe ndị metụtara oke ibu.Ọ nwere mmetụta nke njikwa ịdị arọ ogologo oge (mbelata ibu, mmezi arọ na mgbochi nlọghachi).Ịṅụ ọgwụ ahụ nwere ike ibelata ọnụ ọgụgụ ihe ize ndụ metụtara oke ibu na ọrịa ndị ọzọ metụtara oke ibu, gụnyere hypercholesterolemia na ụdị ọrịa shuga 2.
Orlistat bụ onye na-abụghị CNS na-eme ihe maka ọgwụgwọ oke ibu.Ọ na-eme naanị na eriri afọ tract, na-egbochi hydrolysis nke triacylglycerol n'ime free fatty acids na monoacylglycerides site na igbochi lipase na eriri afọ tract, ibelata absorption nke nri abụba (triacylglycerol) site na eriri afọ mucosa, na-akwalite mkpochapụ nke abụba n'ime ahụ. .Lipase bụ enzyme dị mkpa maka ire ere nke abụba n'ime eriri afọ.Ngwaahịa a nwere ike ijikọta ya na serine residues nke gastric na pancreatic lipase iji mee ka lipase ghara ịrụ ọrụ, nke mere na ọ nweghị ike imebi abụba na nri n'ime acid fatty free ma gbochie ojiji na nnabata nke abụba.
Akpachara anya: 1. Ndị ọrịa buru ibu nwere ụdị ọrịa shuga mellitus nke 2 na-efunahụ ibu mgbe ha gwọchara ngwaahịa a, na-esonyere ya na njikwa glycemic ka mma, yana mkpa ịhazi ọgwụ hypoglycemic iji zere hypoglycemia.
2. Ụmụ nwanyị dị ime na ndị na-enye nwa ara, ụmụaka na-erubeghị afọ 18 na ndị nọ n'afọ iri na ụma amụbeghị maka nchekwa na ịdị irè, ejila ya.
