Indole-3-methanol

Nkọwa dị mkpirikpi:

Indole-3-methanol bụ metabolite osisi ọhụrụ nke abụọ emepụtara na inine cruciferous, nke enwere ike isi na inine cruciferous (dị ka broccoli, radish na kọlịflawa).Indole-3-carbinol bụ ihe na-egbochi akpụ akpụ.Indole-3-carbinol nwere ike igbochi omume na mmepe nke etuto dị iche iche.A na-eji Indole-3-methanol kpuchie poly lactic acid co glycolic acid (PLGA) iji mụọ mmetụta anticancer na ara adenocarcinoma epithelial cell (MCF7), colon adenocarcinoma epithelial cell (Caco2) na prostate cancer epithelial cell (PC3) in vitro.A na-ejikwa ya dị ka onye na-emepụta cytochrome P4501A (CYP1A).

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Nkọwa

Indole-3-methanol (I3C) na-arụ ọrụ aromatic hydrocarbon receptor (AHR) ma mee ka ejide usoro cell G1 na apoptosis.Ya mere, ọ bụ ihe nwere ike igbochi ọrịa kansa.Na mgbakwunye, ọ na-akpalite estradiol metabolism site na-akpali cytochrome P450 enzyme.Ya mere, a na-ewere I3C dị ka ọgwụ chemotherapy dị irè maka ụdị ọrịa cancer dị iche iche, gụnyere ọrịa ara ara, ọrịa prostate, cancer colon na leukemia.Indole-3-methanol nwere ike ịkpalite apoptosis nke mkpụrụ ndụ kansa, nke dị mma na enweghị cytotoxic na sel ndị na-abụghị ụbụrụ.N'ihi arụmọrụ ya dị elu, ihe ndị na-adịghị egbu egbu na nke anụ ahụ, indole-3-methanol nwere ike iji dị ka otu n'ime ndị na-aga maka mgbochi ọrịa cancer na ọgwụ ọgwụgwọ.

Ozi ngwaahịa

Nọmba Cas: 700-06-1

Ịdị ọcha: ≥98%

Usoro: C9H9NO

Formula Wt.Aha: 147.17

Aha Chemical: INDOLE-3-CARBINOL

Okwu okwu: Indole-3-carbinol, 99.5%;Indole-3-carbinol98%;(1H-Indol-3-yl) - methan;Indol-3-yl-methanol;3-INDOLAMETHChemicalbookANOL;INDOLE-3-CARBINOL: 3-INDOLEMETHANOL;INDOLE-3-CARBINOL(RG);3-HYDROXYMETHYLINDOLE(INDOLE-3-CARBINOL)

Ebe mgbaze: 96-99 Celsius

Ebe esi mmiri: 267.28C

Ọdịdị: Gbanyụọ-acha ọcha ruo odo-oroma crystalline ntụ ntụ ma ọ bụ flakes