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Ngwaahịa

Adenosine

Nkọwa dị mkpirikpi:

Aha: Adenosine
Nọmba CAS: 58-61-7
Nọmba nbanye EINECS: 200-389-9
Usoro ihe omimi: C10H13N5O4
Arọ molikula: 267.25


Nkọwa ngwaahịa

Mkpado ngwaahịa

Usoro nhazi

1
Anụ ahụ

Ọdịdị: kristal ọcha ma ọ bụ na-acha ọcha kristal ntụ ntụ
Njupụta: 2.08 g/cm³
Ebe mgbaze: 234 ruo 236 ℃
Isi ihe na-esi ísì: 676.3 ℃
Mgbanwe: 1.907
Ebe ọkụ ọkụ: 362.8 ℃

Data nchekwa
Otu dị ize ndụ.
Nọmba njem ngwongwo dị ize ndụ.
Ngalaba mbukota.

Ngwa
A na-eji Adenosine na-enyere aka iweghachite nkụchi obi nkịtị na ndị nwere ụfọdụ nsogbu ọgba aghara obi.
A na-ejikwa Adenosine eme ihe n'oge ule nrụgide nke obi.
Enwere ike iji Adenosine mee ihe maka ebumnuche edepụtaghị na ntuziaka ọgwụ a.

Adenosine, ihe mejupụtara N-9 nke adenine jikọtara ya na C-1 nke D-ribose site na njikọ β-glycosidic, nwere usoro kemịkalụ C10H13N5O4 na ester phosphate ya bụ adenosine acid.Adenosine bụ nucleoside endogenous nke na-agbasa n'ime mkpụrụ ndụ mmadụ niile ma nwee ike ịbanye na myocardium ozugbo iji mepụta adenosine acid site na phosphorylation, nke na-etinye aka na metabolism ike myocardial, yana ịgbasa arịa ọbara na ịba ụba ọbara.A na-eji ya na ọgwụgwọ nke tachycardia supraventricular.Adenosine nwere mmetụta physiological na usoro obi na ọtụtụ usoro ndị ọzọ na anụ ahụ nke uru ahụ.Adenosine bụ etiti dị mkpa eji na njikọ nke adenosine triphosphate (ATP), adenine, adenosine acid, na adenosine asiaticum.
Ọ bụkwa ihe antiarrhythmic nke na-agbanwe paroxysmal supraventricular tachycardia ka ọ bụrụ ọgba aghara sinus.A na-eji ya maka arrhythmias supraventricular metụtara atrioventricular.Ọgwụgwọ nke angina pectoris, myocardial infarction, akwara obi insufficiency, atherosclerosis, mkpa ọbara mgbali, cerebrovascular ọrịa, post-stroke sequelae, na-aga n'ihu muscle atrophy, wdg A na-ejikwa biochemical ọmụmụ.
Adenosine bụ endogenous purine nucleoside nke na-ebelata AV node conduction, na-egbochi ụzọ AV nodal fold ụzọ, ma na-eweghachi ụda nke sinus nkịtị na ndị ọrịa nwere paroxysmal supraventricular tachycardia (PSVT) (ya na ma ọ bụ na-enweghị preexcitation syndrome).A na-ewere Adenosine ngwa ngwa site na mkpụrụ ndụ ọbara uhie, ya mere ọ nwere obere oge nke ime ihe, yana ọkara ndụ plasma na-erughị 10 s.Ụdị PSVT a na-ahụkarị bụ site na ụzọ retrograde, ya mere adenosine dị irè n'ịkwụsị ụdị arrhythmia a.Na ndị na-abụghị atrial ma ọ bụ sinus node regressive arrhythmias (eg, atrial flutter, atrial fibrillation, atrial tachycardia, ventricular tachycardia), adenosine adịghị akwụsị ha, ma nwere ike na-adịru nwa oge atrioventricular ma ọ bụ ventricular ngọngọ, nke nwere ike inye aka mee nchọpụta dị iche iche.


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