nke
Usoro nhazi
Data nchekwa
Izugbe
Ngwa
metabolite nke Diazepam;o nwere mmetụta anticonvulsant na-esiwanye ike karị.
Ndị na-ahụ maka ọgwụ.Imepụta ọgwụ dịka Librium na Valium.
Mmetụta gburugburu ebe obibi
Dị ntakịrị ihe ize ndụ nye mmiri, ekwela ka ọnụ ọgụgụ na-enweghị isi ma ọ bụ buru ibu banye na mmiri dị n'ime ala, ụzọ mmiri ma ọ bụ usoro nsị, na etinyekwala ihe n'ime gburugburu ebe obibi na-enweghị ikike gọọmentị.
Ngwongwo na nkwụsi ike
Kwụsie ike na ọnọdụ okpomọkụ na nrụgide, zere kọntaktị na oxides
Ụzọ nchekwa
Debe akpa ahụ nke ọma ma chekwaa n'ebe dị jụụ na nke kpọrọ nkụ n'ime akpa juru eju.
Usoro synthesis
(1) Emepụtara site na mmeghachi omume nke p-chloroaniline na benzoyl chloride.Tinye p-chlorobenzene na ite mmeghachi omume nke nwere iko na 70 ° C ma ọ bụ n'okpuru, tinye zinc chloride anhydrous, tinye benzoyl chloride dropwise na mkpali, wee bulie okpomọkụ, jide na 195-205 ° C maka 2h, saa ugboro ise na ya. mmiri ọkụ na 90-95 ° C (okpukpu mmiri na ngwọta ịsacha na-enwetaghachi benzoic acid na zinc chloride) na ihe dịka 100 Celsius, tinye sulfuric acid nwayọọ nwayọọ, jide na 142 ° C maka 40min.A na-ebuli ihe siri ike na mmiri.N'okpuru mkpali, a na-edozi pH na alkali mmiri na-adịghị elu karịa 1 ma kpochaa na 20-25 Celsius C.A na-enwetakwa nzacha ahụ dị ka p-chloroaniline.A na-agwakọta achicha nzacha ma kwụsịtụ n'ime mmiri, a na-ewepụ ya na pH = 6, akọrọ akọrọ, jiri mmiri saa ya ka ọ ghara ịnọpụ iche ma kpọọ nkụ iji nweta ngwaahịa ahụ.Mgbe ahụ tinye 6-7 ugboro ethanol, 6% carbon arụ ọrụ, reflux maka 30min, nyo na crystallize, akọrọ iji nweta ezigbo ngwaahịa.(2) p-Nitrochlorobenzene na cyanobenzyl mgbanaka mgbanaka iji nweta isoxazole, wee mepee mgbanaka ahụ, mbelata iji nweta.