Ngwaahịa
2,6-Di-tert-butyl-4-methylpyridine
Usoro nhazi
Ọdịdị: kristal acicular ọcha
Njupụta: 1,476 g/cm3
Ebe mgbaze: 31-32 ℃
Ebe esi mmiri: 148-153 ℃ (12.6kPa)
Ntụgharị ntụgharị: N20/D 1.4763(lit.)
Ebe ọkụ ọkụ: 183 °F
Ọnọdụ nchekwa: 2-8°C
Ọnụọgụ acidity (pKa): 6.88±0.10 (buru amụma)
Data nchekwa
Ọ bụ nke ibu izugbe
Koodu mpaghara:: 2942000000
Ọnụego nkwụghachi ụtụ nke mbupụ (%): 13%
Ngwa
Organic synthetic intermediate, ihe mgbochi siri ike, nke na-abụghị nke nucleophilic nke na-amata ọdịiche dị n'etiti Brnsted (protonic) na Lewis acids.Na-enyere aka ntụgharị mkpụrụ ndụ dị elu kpọmkwem nke aldehydes1 na ketones1,2 gaa na vinyl triflates.
2,6-Di-tert-butyl-4-methylpyridine bụ organic compound na molekụla usoro C14H23N, ihe dị mkpa etiti na organic njikọ, tumadi na-eji na ọgwụ intermediates, organic synthesis, organic solvents, nwekwara ike tinye n'ọrụ na agba mmepụta, pesticide. mmepụta na isi ísì, wdg.
Usoro mmepụta
1. Mee 2,6 di-tert-butyl-4-methylbenzyl trifluoromethanesulfonate N'ime 100-mL okpukpu atọ nke flask a kwadebere na tube ntinye nitrogen, eriri nrụgide mgbe niile, mmanya na-akpali electromagnetic na ice condenser na tube akọrọ, tinye 24.2 g (0.2 mol) nke trimethylethyl phthalide chloride na 3.7 g (0.05 mol) nke tert-butanol.Ngwakọta mmeghachi omume na-ekpo ọkụ na mmanụ bat ruo 85 Celsius.Mgbe ahụ, etinyere 15 g (0.1 mol) nke trifluoromethanesulfonic acid maka ihe karịrị nkeji iri na ise.A na-aga n'ihu na mmeghachi omume ahụ maka nkeji 10, a na-eme ka ngwaahịa mmeghachi omume na-acha ọkụ ọkụ dị jụụ na ice bat ma wụsa n'ime 100 ml nke ether oyi.A na-enyocha mmiri na-acha nchara nchara wee kpọọ nkụ iji nweta 9.6 g (54%) nke nnu buzz na-egbu oge.(Ọ dịghị ọcha achọrọ: maka nzọụkwụ ọzọ nke nkwadebe, recrystallize ugboro abụọ site na chloroform ka carbon tetrachloride 3:1) gaa na kristal agịga na-enweghị agba.
2. Nkwadebe nke 2,6-Di-tert-butyl-4-methyl-vizine N'okpuru edemede, nkwusioru nke 10 g (0.028 mol) nke nnu nnu nke vizine na 200 mL nke 95% ethanol chilled na 60 ° C bụ. agbakwunyere otu ugboro na 100 ml nke amonia gbanyere mkpọrọgwụ na oyi na-atụ ruo 60 Celsius n'ime flask 1-liter nke ubi.A na-aga n'ihu na mmeghachi omume ahụ na 60 ° C maka nkeji 30 na 40 ° C maka awa 2, n'oge a gbazere nkwusioru ahụ.Mgbe ahụ, a na-awụsa ngwakọta mmeghachi omume n'ime 500 ml nke 2% sodium hydroxide ngwọta nwayọọ nwayọọ na-ekpo ọkụ n'ime ụlọ.Ewepụtara ya na .4-100 ml nke pentane, ihe ndị na-ejikọta ọnụ, 25 ml nke ngwọta sodium chloride saturated saturated, 100 ml nke pentane rotary evaporator concentration.
